Dr. Masharani is an Associate Clinical Professor of Endocrinology and Metabolism in the Department of Medicine, UCSF. He has an active clinical practice treating patients with diabetes and other endocrine disorders. Dr Masharani is a Co-Investigator on a number of NIH funded diabetes studies at UCSF. He is a collaborator on two multi-ethnic studies addressing the interactive relationships among disease management, glycemic control and depression in patients with type 2 diabetes. He is also an investigator for clinical trials evaluating the clinical efficacy of a monoclonal antiCD3 antibody for the maintenance of clinical remission in new onset type 1 diabetes. As a Co-Investigator of the UCSF Islet Transplant Group, Dr Masharani assists in managing diabetes of patients admitted to UCSF for islet transplantation evaluation. He also assists with the tests assessing beta cell function and insulin sensitivity post-transplantation. Dr Masharani is a Co-Investigator on a study evaluating insulin sensitivity, body composition, regional adiposity and changes in the components of the insulin signaling pathway before and after exercise training Dr Masharani supervises the clinical trial in the General Clinical Research Center at UCSF and performs the euglycemic hyperinsulinemic clamps and muscle biopsies.

Publications

• Campos E, Kotite L, Blanche P, Mitsugi Y, Frost PH, Masharani U, Krauss RM, Havel RJ (2002) Properties of triglyceride-rich and cholesterol-rich lipoproteins in the remnant-like particle fraction of human blood plasma. J Lipid Res 43: 365-74.
• Steele C, Hagopian WA, Gitelman S, Masharani U, Cavaghan M, Rother K, Donaldson D, Harlan DM, Bluestone J, Herold KC (2004) Insulin secretion in type 1 diabetes. Diabetes 53:426-433